Precision Medicine

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Precision Medicine is a clinical practice concept used to weigh evidence, patient characteristics, benefits, harms, and uncertainty in care. Reliable conclusions require implementation evidence, shared decision making, and quality measure, while early mechanisms or correlations cannot substitute for validated clinical outcomes.

Evidence relevant to Precision Medicine is organized around patient selection and diagnostic or therapeutic decisions, with separate attention to clinical guidelines. To evaluate patient selection, the discussion considers both patient outcome data and clinical trials and cohort studies; the strongest interpretation still recognizes that individual response and health-system context can limit broad recommendations.